EFAVALEUKIN ALFA
Efavaleukin alfa is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
9 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Graft vs host disease | D006086 | — | D89.81 | 3 | 1 | — | — | — | 3 |
| Bronchiolitis obliterans syndrome | D000092122 | — | — | 3 | 1 | — | — | — | 3 |
| Systemic lupus erythematosus | D008180 | HP_0002725 | M32 | 1 | 1 | — | — | — | 2 |
| Ulcerative colitis | D003093 | EFO_0000729 | K51 | — | 2 | — | — | — | 2 |
| Colitis | D003092 | EFO_0003872 | K52.9 | — | 2 | — | — | — | 2 |
| Ulcer | D014456 | MPATH_579 | — | — | 2 | — | — | — | 2 |
| Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | 1 | 1 | — | — | — | 1 |
| Arthritis | D001168 | HP_0001369 | M05-M14 | 1 | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Myositis | D009220 | EFO_0000783 | G72.49 | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | EFAVALEUKIN ALFA |
| INN | efavaleukin alfa |
| Description | Efavaleukin alfa is an experimental drug that works as an interleukin-2 "mutein Fc fusion protein that preferentially binds the high-affinity IL-2 receptor alpha chain (CD25) to selectively promote Treg expansion". It is developed to treat systemic lupus erythematosus (SLE).
|
| Classification | Protein |
| Drug class | Fc fusion protein; interleukins: interleukin-2 analogues and derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4298204 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | YNH9K62UXU (ChemIDplus, GSRS) |
Target
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Financial
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Trends
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Additional graphs summarizing 21 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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